Buprenorphine Reduces Cerebral Glucose Metabolism in Polydrug Abusers
نویسندگان
چکیده
منابع مشابه
Cerebral glucose metabolism in Fisher syndrome.
BACKGROUND Fisher syndrome (FS) is characterised by a triad of ophthalmoplegia, ataxia and areflexia. The lesion sites responsible for ataxia and ophthalmoplegia in FS require further exploration. The aim of this study was to determine the involvement of the central nervous system in FS using (18)F-fluorodeoxyglucose-positron emission tomography (FDG-PET). METHODS Cerebral glucose metabolism ...
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Positron emission tomography (PET) is a nuclear imaging technique that can be employed to assess regional brain function noninvasively. When used with [18F]fluorodeoxyglucose (FDG), a radiotracer for glucose metabolism, it can provide quantitative maps of global and regional cerebral metabolic rates for glucose (Phelps et al. 1979; Reivich et al. 1979). The FDG method has been used to assess ch...
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Several sources indicate that intravenously administered buprenorphine may have significant abuse liability in humans. The present study evaluated the reinforcing effects of intravenously administered buprenorphine (0, 2, and 8 mg) in detoxified heroin-dependent participants during a 7.5-week inpatient study. Participants (n = 6) were detoxified from heroin over a 1.5-week period immediately af...
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ژورنال
عنوان ژورنال: Neuropsychopharmacology
سال: 1994
ISSN: 0893-133X,1740-634X
DOI: 10.1038/npp.1994.18